Sunday, March 31, 2019

Treatments for Type 1 Diabetes

Treatments for Type 1 DiabetesType 1 Diabetes, which norm wholey called as juvenile onset or Insulin-Dependent Diabetes Mellitus (IDDM) are usually appear during childhood, juvenile years, or early adulthood(7,8).In the Islet cell of pancreas, Beta makes insulin. It is an autoimmune infirmity meaning that immune system allow for destroys beta cell, thence insulin can non be produced. As a result the cells in our bodies depart not be able to process the glucose and therefore drive home no vigour for movement (21) . Moreover, the glucose is unable to be transferred from short letterstream to the cells and the glucose train will augment in the seam compared to normal. Main symptoms include blurred vision, passing piddle more often than usual and unusual thirst(8).The problemDiabetes was the seventh leaders grounds of death listed on U.S. death certificates in 2006. This ranking is found on the 72,507 death certificates in 2006 in which diabetes was listed as the underly ing campaign of death (11). Moreover, IDDM cannot be prevented as it mostly inherited by the parent cell as the research said if you have a family member with Type 1 Diabetes, your risk is or so five to hexad percent, compared to the risk in general population which is 0.4%(2). Hence what are attainable grapplements to re go forth the insulin to minimise the rise of glucose level in the blood?(248 words)A POSSIBLE SOLUTIONInsulin kernel therapyInsulin pump is a small automatonlike device, a little larger than a p climb onr that is worn foreign the body, often on a belt or in a pocket (13). It will deliver insulin through cannula on the infusion come in and the patients have to decide how much insulin will be given as it is not automatic.Nipro Diabetes Systems Amigo OmniPod Insulin Management SystemThe goal of insulin pump therapy is to imitate the insulin discrimination pattern which can be seen in people without diabetes. Two patterns released by insulin areBasal insulin is insulin that is delivered continuously in small amounts.Bolus insulin, which is extra process insulin released for controlling the glucose level later taking meals (2).(388 words)Standard bolus indicates insulin is pumped wholly and diffuses at the onset of bolus. Spike shape was pumped which expected to coiffure the fastest possible for that kind of insulin. Hence, they must(prenominal) oblige meals which contain amply carb and low protein and fat in tell apart to lowers the blood sugar levels quickly. panoptic bolus represents the spreading of insulin over time by slow infusion. By pumping forthrightly pother shape, the bolus is avoiding a high initial dose of insulin entering the blood causing low blood sugar level before digestion. Therefore, they should take more high fat high protein meals such as steak, which will be raising blood sugar for many hours past onset of the shape.Figure is a combination bolus of spike shape and square wave shape (12).Combo bolus.JPGTh is will give larger dose of insulin at introductory and extent the tails of insulin do. As a result, those who have combination bolus are appropriate for high fat meals such as pizza and chocolate cake.(608 words)This method can increase the spike bolus action and extend the action for several hours. Thus, super bolus people must take certain foods (like sugar-coated breakfast cereals) which cause a large post-prandial peak of blood sugar. It attacks the blood sugar peak with the fastest delivery of insulin that can be much achieved by pumping.In the year 2009, round 1119 pumpers are recorded in United State and this is the one of the solution for mimicking the production of insulin in the body. The age group ranging from 0 to 20 shows the highest user of insulin pump hence it is proved that diabetes type 1 usually appear in childhood and teenaged years.(767 words)Over the years, a number of different types and brands of insulin have been developed to endure different needs. SOCIAL AND ECONOMICAL IMPLICATIONSKatherine G who was diagnosed with diabetes and keep a pare downg what had I done wrong? And wanted to smack every overweight psyche she saw. From Gretchen Becker The First Year Type 2 Diabetes copyright 2001(1).First and foremost, after(prenominal) being diagnosed as diabetic, almost of them cannot accept the fact and take some time to mourn their loss. near of them might fell depressed for manakinIn 2007, the world is estimated to spend at least USD 232 billion to treat and prevent diabetes and its forkings. By 2025, this lower-bound estimate will exceed USD 302.5 billion. writer http//www.worlddiabetesday.org/files/docs/Economic_aspects.pdf(15)They in like manner worried about the next generation as Type 1 Diabetes is inherited and get stress thinking about the complication of diabetes which cause them to use wheelchair because has no feet and likewise being wheeled in distinguish to use the dialysis machine(1,5). They may lose their self esteem to face the world. Some might be under squelch as they have to be strict on their food intake and must follow the nutrition for diabetic. Moreover, they need to take a lot of medicine and withal insertion.From this statement, I can concluded that diabetes is a highly cost disease. First and foremost, the insulin pump therapy itself is a very expensive and a lot of money spends for buy the insulin needed for pumping. Secondly, diabetes has long term complications which are dangerous for instance retinopathy, neuropathy and alike kidney failure. They must use a lot of money in order to prevent these complications from spreading at their body. As we all inhabit, not all diabetic people are wealth and they only depend on only one income source, hence can we imagine how they would survive with this disease especially those from the poorest countries and family. (15)(1307 words)BENEFIT AND RISKAdvantagesBEST hbA1cs before the pumpThe level of hbA1C decreases with an aver age of 6.3 after using the insulin pump compared to 7.2 before using the pump. The pumper users also show decreasing pattern from 725 to 713. So, the percentage of getting long-term complication for instance stroke, snapper disease, blindness, kidney failure and also amputation can be lowered.(1383 words)Pumpers have been shown to experience lesser episodes of severe hypoglycaemia compared to people who take injections. clinical studies shown that using fast playacting insulin, the glucose control can be meliorate with less risk of hypoglycaemia (3,22). Moreover, the pumper can keep up-to-date with their everyday schedule. They are flexible to move and free to do what they want for pillowcase they can keep on the pump during exercising in the evening. Insulin pumpers must change the infusion site about three times a week, and using about only 156 insertion a year and the injection can achieved mean more than 1,400 injection per year. (3,22)(1527 words)DisadvantagesAn episode of diabetic ketoacidosis state of inadequate insulin levels resulting in high blood pressure and accumulation of organic acids and ketones in the blood may take place if the pumpers do not receive sufficient amount of fast acting insulin for many hours. There is high risk of infection if the catheter site of cannula has not been changed every three days and also skin reactions such as rashes may appear at the site of cannula. This therapy is very expensive as pumps are high prices. By using insulin therapy, the society might know that you have diabetes since this is one of the popular ways to cure it (19) . Some of diabetic might develop blurring vision soon after starting insulin ascribable to a change of lens refraction and it will correct itself indoors two to three weeks (3) .The picture 2 shows the process of forming of diabetic ketoacidosis. Source http//www.deo.ucsf.edu/type2/diabetes-treatment/complications/diabetic-ketoacidosis.html(1669 words)ALTERNATIVE SOLUTIONSExerci singPeople, who exercise regularly, when compared to those who do not exercise, decrease their pass off of developing diabetes by 30 to 50%. Exercise help by improving the bodys to use insulin and causes cholesterol level and blood pressure to dissolve (4). Aerobic exercise burns calories to help in managing the weight, strengthen the heart and lungs and gives endurance. In other word, it improves the bodys ability to use insulin and prevent diabetes. We must do warm up and cool down before and after exercising. wee-wee at least 20 minutes and three times a week to exercise. Furthermore exercise can increase the uptake of glucose by muscles thus increase in carbohydrate intake. We must take nice carbohydrate before exercising but overdose of carbohydrate will results in hyperglycaemia. As diabetes, insulin must be sufficient before and after exercise because strenuous exercise and insufficient insulin will worsen diabetic control (5).Supplement vitamin and herbsVitamin E helps d issolve fresh clot in veins and reduce the oxygen requirement of tissue and cell. Moreover, it also helps to from new skin (in healing the ulcer and burns) and increases the blood supply to tissue, thus reduces diabetes gangrene and amputations. Vitamin E reduces the need for insulin in 30% of diabetes (6).Biotin is B vitamin that functions in conciliate and use of carbohydrate, fat and amino acids. It enhances insulin sensitivity and increase the activity of enzyme glucokinase, enzyme responsible for the first step in the use of glucose in liver as this enzyme is low in diabetic. It also helps in the treatment of diabetic neuropathy (7).(1937 words)EVALUATIONS through the years, we have introduced valuable solutions for patients and healthcare professionals-including continuous glucose monitoring (CGM), CareLink Therapy Management bundle and the MiniMed Paradigm REAL-Time System, the worlds first integrated insulin pump and CGM System. Source http//www.minimed.com/about/index.ht ml (22)From the book of Diabetes Demystified written by Masharani, M.D copyright 2008(2) provide us a brief about diabetes. It helps us to know well about diabetes and wherefore they have this disease. Moreover, ways of taking care for diabetic people also included and it provides me with the chart and also graphs for better understanding. The info are also available in the other books (1,4,5,6,7,8).Hence the facts are vertical. However, the publishing date was 2008 and the information might not be updated.I believe this website has given me reliable and factual data. This is because it is owned by Medtronic Minimed, Incoporation and has been updated the info this year, 2010. Furthermore, they had led the technology about insulin pump therapy for 25 years and pioneered it since 1983. It helps pumpers to understand better about good control, insulin pump therapy and why pump therapy rather than the other.(2168 words)

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